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Towards Profiles of Resistance Development and Toxicity for the Small Cationic Hexapeptide RWRWRW-NH(2)
RWRWRW-NH(2) (MP196) is an amphipathic hexapeptide that targets the bacterial cytoplasmic membrane and inhibits cellular respiration and cell wall synthesis. In previous studies it showed promising activity against Gram-positive bacteria and no significant cytotoxicity or hemolysis. MP196 is therefo...
Autores principales: | Wenzel, Michaela, Prochnow, Pascal, Mowbray, Catherine, Vuong, Cuong, Höxtermann, Stefan, Stepanek, Jennifer J., Albada, H. Bauke, Hall, Judith, Metzler-Nolte, Nils, Bandow, Julia E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999427/ https://www.ncbi.nlm.nih.gov/pubmed/27617260 http://dx.doi.org/10.3389/fcell.2016.00086 |
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