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A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

Fatty acid metabolism is an important feature of the pathogenicity of Mycobacterium tuberculosis during infection. Consumption of fatty acids requires regulation of carbon flux bifurcation between the oxidative TCA cycle and the glyoxylate shunt. In Escherichia coli, flux bifurcation is regulated by...

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Detalles Bibliográficos
Autores principales: Murima, Paul, Zimmermann, Michael, Chopra, Tarun, Pojer, Florence, Fonti, Giulia, Dal Peraro, Matteo, Alonso, Sylvie, Sauer, Uwe, Pethe, Kevin, McKinney, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999502/
https://www.ncbi.nlm.nih.gov/pubmed/27555519
http://dx.doi.org/10.1038/ncomms12527