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LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression

Liver cancer has a tendency to develop asymptomatically in patients, so most patients are diagnosed at a later stage. Accumulating evidence implicates that liver tumour-initiating cells (TICs) as being responsible for liver cancer initiation and recurrence. However, the molecular mechanism of liver...

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Detalles Bibliográficos
Autores principales: Chen, Zhen-zhen, Huang, Lan, Wu, Ya-hong, Zhai, Wen-jie, Zhu, Ping-ping, Gao, Yan-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999516/
https://www.ncbi.nlm.nih.gov/pubmed/27553854
http://dx.doi.org/10.1038/ncomms12598