Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages

Microcephaly is a cortical malformation disorder characterized by an abnormally small brain. Recent studies have revealed severe cases of microcephaly resulting from human mutations in the NDE1 gene, which is involved in the regulation of cytoplasmic dynein. Here using in utero electroporation of ND...

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Detalles Bibliográficos
Autores principales: Doobin, David J., Kemal, Shahrnaz, Dantas, Tiago J., Vallee, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999518/
https://www.ncbi.nlm.nih.gov/pubmed/27553190
http://dx.doi.org/10.1038/ncomms12551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999518/
https://www.ncbi.nlm.nih.gov/pubmed/27553190
http://dx.doi.org/10.1038/ncomms12551

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