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Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages
Microcephaly is a cortical malformation disorder characterized by an abnormally small brain. Recent studies have revealed severe cases of microcephaly resulting from human mutations in the NDE1 gene, which is involved in the regulation of cytoplasmic dynein. Here using in utero electroporation of ND...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999518/ https://www.ncbi.nlm.nih.gov/pubmed/27553190 http://dx.doi.org/10.1038/ncomms12551 |