Cargando…

Characterizing the Developmental Trajectory of Sirolimus Clearance in Neonates and Infants

Sirolimus is increasingly being used in neonates and infants, but the mechanistic basis of age‐dependent changes in sirolimus disposition has not been fully addressed yet. In order to characterize the age‐dependent changes, serial sirolimus clearance (CL) estimates in individual young pediatric pati...

Descripción completa

Detalles Bibliográficos
Autores principales: Emoto, C, Fukuda, T, Mizuno, T, Schniedewind, B, Christians, Uwe, Adams, DM, Vinks, AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999604/
https://www.ncbi.nlm.nih.gov/pubmed/27501453
http://dx.doi.org/10.1002/psp4.12096