A Systems Model for Ursodeoxycholic Acid Metabolism in Healthy and Patients With Primary Biliary Cirrhosis

A systems model was developed to describe the metabolism and disposition of ursodeoxycholic acid (UDCA) and its conjugates in healthy subjects based on pharmacokinetic (PK) data from published studies in order to study the distribution of oral UDCA and potential interactions influencing therapeutic...

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Detalles Bibliográficos
Autores principales: Zuo, P, Dobbins, RL, O'Connor‐Semmes, RL, Young, MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999605/
https://www.ncbi.nlm.nih.gov/pubmed/27537780
http://dx.doi.org/10.1002/psp4.12100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999605/
https://www.ncbi.nlm.nih.gov/pubmed/27537780
http://dx.doi.org/10.1002/psp4.12100

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