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Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

Proliferation and spatial development of colonic epithelial cells are highly regulated along the crypt vertical axis, which, when perturbed, can result in aberrant growth and carcinogenesis. In this study, two key factors were identified that have important and counterbalancing roles regulating thes...

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Detalles Bibliográficos
Autores principales: Uchiyama, Kazuhiko, Sakiyama, Toshio, Hasebe, Takumu, Musch, Mark W., Miyoshi, Hiroyuki, Nakagawa, Yasushi, He, Tong-Chuan, Lichtenstein, Lev, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu, Jabri, Bana, Stappenbeck, Thaddeus, Chang, Eugene B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999796/
https://www.ncbi.nlm.nih.gov/pubmed/27561676
http://dx.doi.org/10.1038/srep32094