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Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development
Proliferation and spatial development of colonic epithelial cells are highly regulated along the crypt vertical axis, which, when perturbed, can result in aberrant growth and carcinogenesis. In this study, two key factors were identified that have important and counterbalancing roles regulating thes...
Autores principales: | Uchiyama, Kazuhiko, Sakiyama, Toshio, Hasebe, Takumu, Musch, Mark W., Miyoshi, Hiroyuki, Nakagawa, Yasushi, He, Tong-Chuan, Lichtenstein, Lev, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu, Jabri, Bana, Stappenbeck, Thaddeus, Chang, Eugene B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999796/ https://www.ncbi.nlm.nih.gov/pubmed/27561676 http://dx.doi.org/10.1038/srep32094 |
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