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Imbalance between Glutamate and GABA in Fmr1 Knockout Astrocytes Influences Neuronal Development

Fragile X syndrome (FXS) is a form of inherited mental retardation that results from the absence of the fragile X mental retardation protein (FMRP), the product of the Fmr1 gene. Numerous studies have shown that FMRP expression in astrocytes is important in the development of FXS. Although astrocyte...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Wang, Yan, Zhou, Shimeng, Yang, Liukun, Shi, Qixin, Li, Yujiao, Zhang, Kun, Yang, Le, Zhao, Minggao, Yang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999833/
https://www.ncbi.nlm.nih.gov/pubmed/27517961
http://dx.doi.org/10.3390/genes7080045