Telomere Transcripts Target Telomerase in Human Cancer Cells

Long non-coding transcripts from telomeres, called telomeric repeat-containing RNA (TERRA), were identified as blocking telomerase activity (TA), a telomere maintenance mechanism (TMM), in tumors. We expressed recombinant TERRA transcripts in tumor cell lines with TA and with alternative lengthening...

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Detalles Bibliográficos
Autores principales: Kreilmeier, Theresa, Mejri, Doris, Hauck, Marlene, Kleiter, Miriam, Holzmann, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999834/
https://www.ncbi.nlm.nih.gov/pubmed/27537914
http://dx.doi.org/10.3390/genes7080046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999834/
https://www.ncbi.nlm.nih.gov/pubmed/27537914
http://dx.doi.org/10.3390/genes7080046

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