Transcriptional Reactivation of the FMR1 Gene. A Possible Approach to the Treatment of the Fragile X Syndrome†

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability, caused by CGG expansion over 200 repeats (full mutation, FM) at the 5′ untranslated region (UTR) of the fragile X mental retardation 1 (FMR1) gene and subsequent DNA methylation of the promoter region, accompanie...

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Detalles Bibliográficos
Autores principales: Tabolacci, Elisabetta, Palumbo, Federica, Nobile, Veronica, Neri, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999837/
https://www.ncbi.nlm.nih.gov/pubmed/27548224
http://dx.doi.org/10.3390/genes7080049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999837/
https://www.ncbi.nlm.nih.gov/pubmed/27548224
http://dx.doi.org/10.3390/genes7080049

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