Hydrolytic Fate of 3/15-Acetyldeoxynivalenol in Humans: Specific Deacetylation by the Small Intestine and Liver Revealed Using in Vitro and ex Vivo Approaches

In addition to deoxynivalenol (DON), acetylated derivatives, i.e., 3-acetyl and 15-acetyldexynivalenol (or 3/15ADON), are present in cereals leading to exposure to these mycotoxins. Animal and human studies suggest that 3/15ADON are converted into DON after their ingestion through hydrolysis of the...

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Detalles Bibliográficos
Autores principales: Ajandouz, El Hassan, Berdah, Stéphane, Moutardier, Vincent, Bege, Thierry, Birnbaum, David Jérémie, Perrier, Josette, Di Pasquale, Eric, Maresca, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999848/
https://www.ncbi.nlm.nih.gov/pubmed/27483321
http://dx.doi.org/10.3390/toxins8080232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999848/
https://www.ncbi.nlm.nih.gov/pubmed/27483321
http://dx.doi.org/10.3390/toxins8080232

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