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Mechanism of Action and Clinical Potential of Fingolimod for the Treatment of Stroke

Fingolimod (FTY720) is an orally bio-available immunomodulatory drug currently approved by the FDA for the treatment of multiple sclerosis. Currently, there is a significant interest in the potential benefits of FTY720 on stroke outcomes. FTY720 and the sphingolipid signaling pathway it modulates ha...

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Detalles Bibliográficos
Autores principales: Li, Wentao, Xu, Haoliang, Testai, Fernando D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999895/
https://www.ncbi.nlm.nih.gov/pubmed/27617002
http://dx.doi.org/10.3389/fneur.2016.00139