A High-Content, Phenotypic Screen Identifies Fluorouridine as an Inhibitor of Pyoverdine Biosynthesis and Pseudomonas aeruginosa Virulence

Pseudomonas aeruginosa is an opportunistic pathogen that causes severe health problems. Despite intensive investigation, many aspects of microbial virulence remain poorly understood. We used a high-throughput, high-content, whole-organism, phenotypic screen to identify small molecules that inhibit P...

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Detalles Bibliográficos
Autores principales: Kirienko, Daniel R., Revtovich, Alexey V., Kirienko, Natalia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999921/
https://www.ncbi.nlm.nih.gov/pubmed/27579370
http://dx.doi.org/10.1128/mSphere.00217-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999921/
https://www.ncbi.nlm.nih.gov/pubmed/27579370
http://dx.doi.org/10.1128/mSphere.00217-16

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