Pubertal Expression of α4βδ GABA(A) Receptors Reduces Seizure-Like Discharges in CA1 Hippocampus

More than half of children with epilepsy outgrow their seizures, yet the underlying mechanism is unknown. GABAergic inhibition increases at puberty in female mice due to expression of extrasynaptic α4βδ GABA(A) receptors (GABARs). Therefore, we tested the role of these receptors in regulating seizur...

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Detalles Bibliográficos
Autores principales: Yang, Lie, Shen, Hui, Merlin, Lisa R., Smith, Sheryl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999950/
https://www.ncbi.nlm.nih.gov/pubmed/27561815
http://dx.doi.org/10.1038/srep31928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999950/
https://www.ncbi.nlm.nih.gov/pubmed/27561815
http://dx.doi.org/10.1038/srep31928

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