BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality

A delay in liver regeneration after partial hepatectomy (PHx) leads to acute liver injury, and such delays are frequently observed in aged patients. BubR1 (budding uninhibited by benzimidazole-related 1) controls chromosome mitotic segregation through the spindle assembly checkpoint, and BubR1 down-...

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Detalles Bibliográficos
Autores principales: Ikawa-Yoshida, Ayae, Matsumoto, Takuya, Okano, Shinji, Aoyagi, Yukihiko, Matsubara, Yutaka, Furuyama, Tadashi, Nakatsu, Yoshimichi, Tsuzuki, Teruhisa, Onimaru, Mitsuho, Ohkusa, Tomoko, Nomura, Masatoshi, Maehara, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999951/
https://www.ncbi.nlm.nih.gov/pubmed/27561386
http://dx.doi.org/10.1038/srep32399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999951/
https://www.ncbi.nlm.nih.gov/pubmed/27561386
http://dx.doi.org/10.1038/srep32399

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