Cohort Multiple Randomised Controlled Trials (cmRCT) design: efficient but biased? A simulation study to evaluate the feasibility of the Cluster cmRCT design

BACKGROUND: The Cohort Multiple Randomised Controlled Trial (cmRCT) is a newly proposed pragmatic trial design; recently several cmRCT have been initiated. This study tests the unresolved question of whether differential refusal in the intervention arm leads to bias or loss of statistical power and...

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Detalles Bibliográficos
Autores principales: Pate, Alexander, Candlish, Jane, Sperrin, Matthew, Van Staa, Tjeerd Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000409/
https://www.ncbi.nlm.nih.gov/pubmed/27566594
http://dx.doi.org/10.1186/s12874-016-0208-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000409/
https://www.ncbi.nlm.nih.gov/pubmed/27566594
http://dx.doi.org/10.1186/s12874-016-0208-1

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