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High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

BACKGROUND: The progression of colorectal cancer (CRC) involves recurrent amplifications/mutations in the epidermal growth factor receptor (EGFR) and downstream signal transducers of the Ras pathway, KRAS and BRAF. Whether genetic events predicted to result in increased and constitutive signaling in...

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Detalles Bibliográficos
Autores principales: Padhan, Narendra, Nordling, Torbjörn E. M., Sundström, Magnus, Åkerud, Peter, Birgisson, Helgi, Nygren, Peter, Nelander, Sven, Claesson-Welsh, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000422/
https://www.ncbi.nlm.nih.gov/pubmed/27562229
http://dx.doi.org/10.1186/s12885-016-2725-z