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High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
BACKGROUND: The progression of colorectal cancer (CRC) involves recurrent amplifications/mutations in the epidermal growth factor receptor (EGFR) and downstream signal transducers of the Ras pathway, KRAS and BRAF. Whether genetic events predicted to result in increased and constitutive signaling in...
Autores principales: | Padhan, Narendra, Nordling, Torbjörn E. M., Sundström, Magnus, Åkerud, Peter, Birgisson, Helgi, Nygren, Peter, Nelander, Sven, Claesson-Welsh, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000422/ https://www.ncbi.nlm.nih.gov/pubmed/27562229 http://dx.doi.org/10.1186/s12885-016-2725-z |
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