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Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis

The protozoan parasite Trypanosoma brucei causes the fatal illness human African trypanosomiasis (HAT). Standard of care medications currently used to treat HAT have severe limitations, and there is a need to find new chemical entities that are active against infections of T. brucei. Following a “dr...

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Detalles Bibliográficos
Autores principales: Thomas, Sarah M., Purmal, Andrei, Pollastri, Michael, Mensa-Wilmot, Kojo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000474/
https://www.ncbi.nlm.nih.gov/pubmed/27561392
http://dx.doi.org/10.1038/srep32083