TGFβ-induced switch from adipogenic to osteogenic differentiation of human mesenchymal stem cells: identification of drug targets for prevention of fat cell differentiation

BACKGROUND: Patients suffering from osteoporosis show an increased number of adipocytes in their bone marrow, concomitant with a reduction in the pool of human mesenchymal stem cells (hMSCs) that are able to differentiate into osteoblasts, thus leading to suppressed osteogenesis. METHODS: In order t...

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Detalles Bibliográficos
Autores principales: van Zoelen, Everardus J., Duarte, Isabel, Hendriks, José M., van der Woning, Sebastian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000485/
https://www.ncbi.nlm.nih.gov/pubmed/27562730
http://dx.doi.org/10.1186/s13287-016-0375-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000485/
https://www.ncbi.nlm.nih.gov/pubmed/27562730
http://dx.doi.org/10.1186/s13287-016-0375-3

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