A novel three-way rearrangement involving ETV6 (12p13) and ABL1 (9q34) with an unknown partner on 3p25 resulting in a possible ETV6-ABL1 fusion in a patient with acute myeloid leukemia: a case report and a review of the literature

BACKGROUND: Acute myeloid leukemia (AML) is commonly characterized by several chromosomal abnormalities resulting in the formation of chimeric genes that play various roles in leukemogenesis. Translocations resulting in the ETV6-ABL1 fusion gene are rare in AML and other hematologic malignancies wit...

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Detalles Bibliográficos
Autores principales: Tirado, Carlos A., Siangchin, Ken, Shabsovich, David S., Sharifian, Maryam, Schiller, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000511/
https://www.ncbi.nlm.nih.gov/pubmed/27570624
http://dx.doi.org/10.1186/s40364-016-0070-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000511/
https://www.ncbi.nlm.nih.gov/pubmed/27570624
http://dx.doi.org/10.1186/s40364-016-0070-7

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