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Homocysteine Aggravates Cortical Neural Cell Injury through Neuronal Autophagy Overactivation following Rat Cerebral Ischemia-Reperfusion

Elevated homocysteine (Hcy) levels have been reported to be involved in neurotoxicity after ischemic stroke. However, the underlying mechanisms remain incompletely understood to date. In the current study, we hypothesized that neuronal autophagy activation may be involved in the toxic effect of Hcy...

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Detalles Bibliográficos
Autores principales: Zhao, Yaqian, Huang, Guowei, Chen, Shuang, Gou, Yun, Dong, Zhiping, Zhang, Xumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000594/
https://www.ncbi.nlm.nih.gov/pubmed/27455253
http://dx.doi.org/10.3390/ijms17081196