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Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

The development of pharmacotherapeutics that reduce relapse to alcohol drinking in patients with alcohol dependence is of considerable research interest. Preclinical data support a role for nucleus accumbens (NAc) κ opioid receptors (KOR) in chronic intermittent ethanol (CIE) exposure-induced increa...

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Detalles Bibliográficos
Autores principales: Rose, Jamie H., Karkhanis, Anushree N., Steiniger-Brach, Björn, Jones, Sara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000614/
https://www.ncbi.nlm.nih.gov/pubmed/27472317
http://dx.doi.org/10.3390/ijms17081216