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Is Upregulation of Aquaporin 4-M1 Isoform Responsible for the Loss of Typical Orthogonal Arrays of Particles in Astrocytomas?

The astrocytic endfoot membranes of the healthy blood-brain barrier—contacting the capillary—are covered with a large number of the water channel aquaporin 4 (AQP4). They form orthogonal arrays of particles (OAPs), which consist of AQP4 isoform M1 and M23. Under pathologic conditions, AQP4 is distri...

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Detalles Bibliográficos
Autores principales: Fallier-Becker, Petra, Nieser, Maike, Wenzel, Ulrike, Ritz, Rainer, Noell, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000628/
https://www.ncbi.nlm.nih.gov/pubmed/27483250
http://dx.doi.org/10.3390/ijms17081230