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Droplet Digital PCR Based Androgen Receptor Variant 7 (AR-V7) Detection from Prostate Cancer Patient Blood Biopsies

Androgen receptor splice variant V7 (AR-V7) was recently identified as a valuable predictive biomarker in metastatic castrate-resistant prostate cancer. Here, we report a new, sensitive and accurate screen for AR-V7 mRNA expression directly from circulating tumor cells (CTCs): We combined EpCAM-base...

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Detalles Bibliográficos
Autores principales: Ma, Yafeng, Luk, Alison, Young, Francis P., Lynch, David, Chua, Wei, Balakrishnar, Bavanthi, de Souza, Paul, Becker, Therese M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000662/
https://www.ncbi.nlm.nih.gov/pubmed/27527157
http://dx.doi.org/10.3390/ijms17081264