Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

Obesity and insulin resistance are associated with oxidative stress (OS). The causal role of adipose OS in the pathogenesis of these conditions is unknown. To address this issue, we generated mice with an adipocyte-selective deletion of manganese superoxide dismutase (MnSOD). When fed a high-fat die...

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Detalles Bibliográficos
Autores principales: Han, Yong Hwan, Buffolo, Márcio, Pires, Karla Maria, Pei, Shaobo, Scherer, Philipp E., Boudina, Sihem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001177/
https://www.ncbi.nlm.nih.gov/pubmed/27284109
http://dx.doi.org/10.2337/db16-0283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001177/
https://www.ncbi.nlm.nih.gov/pubmed/27284109
http://dx.doi.org/10.2337/db16-0283

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