Protein Phosphatase 1-α Regulates AS160 Ser(588) and Thr(642) Dephosphorylation in Skeletal Muscle

Akt substrate of 160 kDa (AS160) phosphorylation on Thr(642) and Ser(588) by Akt is essential for insulin’s full effect on glucose transport. However, protein phosphorylation is determined by the balance of actions by kinases and phosphatases, and the specific phosphatase(s) controlling AS160 dephos...

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Detalles Bibliográficos
Autores principales: Sharma, Pragya, Arias, Edward B., Cartee, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001182/
https://www.ncbi.nlm.nih.gov/pubmed/27246912
http://dx.doi.org/10.2337/db15-0867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001182/
https://www.ncbi.nlm.nih.gov/pubmed/27246912
http://dx.doi.org/10.2337/db15-0867

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