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Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network
BACKGROUND: In combination with gene expression profiles, the protein interaction network (PIN) constructs a dynamic network that includes multiple functional modules. Previous studies have demonstrated that rifampin can influence drug metabolism by regulating drug-metabolizing enzymes, transporters...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001204/ https://www.ncbi.nlm.nih.gov/pubmed/27557147 http://dx.doi.org/10.1186/s12864-016-2909-6 |