Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation

Glutamate stimulates ventral midbrain (VM) N-Methyl-D-Aspartate receptors (NMDAR) to initiate dopamine (DA) burst firing activity, a mode of discharge associated with enhanced DA release and reward. Blockade of VM NMDAR, however, enhances brain stimulation reward (BSR), the results can be explained...

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Detalles Bibliográficos
Autores principales: Hernandez, Giovanni, Cossette, Marie-Pierre, Shizgal, Peter, Rompré, Pierre-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001228/
https://www.ncbi.nlm.nih.gov/pubmed/27616984
http://dx.doi.org/10.3389/fnbeh.2016.00161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001228/
https://www.ncbi.nlm.nih.gov/pubmed/27616984
http://dx.doi.org/10.3389/fnbeh.2016.00161

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