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Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation

Glutamate stimulates ventral midbrain (VM) N-Methyl-D-Aspartate receptors (NMDAR) to initiate dopamine (DA) burst firing activity, a mode of discharge associated with enhanced DA release and reward. Blockade of VM NMDAR, however, enhances brain stimulation reward (BSR), the results can be explained...

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Detalles Bibliográficos
Autores principales:	Hernandez, Giovanni, Cossette, Marie-Pierre, Shizgal, Peter, Rompré, Pierre-Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001228/ https://www.ncbi.nlm.nih.gov/pubmed/27616984 http://dx.doi.org/10.3389/fnbeh.2016.00161

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