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Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

BACKGROUND: Somatic mutations can be used as potential biomarkers for subtyping and predicting outcomes for cancer patients. However, cancer patients often carry many somatic mutations, which do not always concentrate on specific genomic loci, suggesting that the mutations may affect common pathways...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Abrams, Zachary, Parvin, Jeffrey D., Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001235/
https://www.ncbi.nlm.nih.gov/pubmed/27556157
http://dx.doi.org/10.1186/s12864-016-2902-0