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Improving alignment accuracy on homopolymer regions for semiconductor-based sequencing technologies

BACKGROUND: Ion Torrent and Ion Proton are semiconductor-based sequencing technologies that feature rapid sequencing speed and low upfront and operating costs, thanks to the avoidance of modified nucleotides and optical measurements. Despite of these advantages, however, Ion semiconductor sequencing...

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Detalles Bibliográficos
Autores principales: Feng, Weixing, Zhao, Sen, Xue, Dingkai, Song, Fengfei, Li, Ziwei, Chen, Duojiao, He, Bo, Hao, Yangyang, Wang, Yadong, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001236/
https://www.ncbi.nlm.nih.gov/pubmed/27556417
http://dx.doi.org/10.1186/s12864-016-2894-9