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Improving alignment accuracy on homopolymer regions for semiconductor-based sequencing technologies
BACKGROUND: Ion Torrent and Ion Proton are semiconductor-based sequencing technologies that feature rapid sequencing speed and low upfront and operating costs, thanks to the avoidance of modified nucleotides and optical measurements. Despite of these advantages, however, Ion semiconductor sequencing...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001236/ https://www.ncbi.nlm.nih.gov/pubmed/27556417 http://dx.doi.org/10.1186/s12864-016-2894-9 |