Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study

BACKGROUND: Tumor suppressor genes (TSGs) encode the guardian molecules to control cell growth. The genomic alteration of TSGs may cause tumorigenesis and promote cancer progression. So far, investigators have mainly studied the functional effects of somatic single nucleotide variants in TSGs. Copy...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001246/
https://www.ncbi.nlm.nih.gov/pubmed/27556634
http://dx.doi.org/10.1186/s12864-016-2904-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001246/
https://www.ncbi.nlm.nih.gov/pubmed/27556634
http://dx.doi.org/10.1186/s12864-016-2904-y

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