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Combined expression of miR-34a and Smac mediated by oncolytic vaccinia virus synergistically promote anti-tumor effects in Multiple Myeloma

Despite great progress made in the treatment of multiple myeloma (MM), it is still incurable. Promising phase II clinical results have been reported recently for oncolytic vaccinia virus (OVV) clinic therapeutics. One reason for this has focused on the critical therapeutic importance of the immune r...

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Detalles Bibliográficos
Autores principales: Lei, Wen, Wang, Shibing, Yang, Chunmei, Huang, Xianbo, Chen, Zhenzhen, He, Wei, Shen, Jianping, Liu, Xinyuan, Qian, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001249/
https://www.ncbi.nlm.nih.gov/pubmed/27552933
http://dx.doi.org/10.1038/srep32174