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Transcriptional gene silencing in humans

It has been over a decade since the first observation that small non-coding RNAs can functionally modulate epigenetic states in human cells to achieve functional transcriptional gene silencing (TGS). TGS is mechanistically distinct from the RNA interference (RNAi) gene-silencing pathway. TGS can res...

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Detalles Bibliográficos
Autores principales: Weinberg, Marc S., Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001580/
https://www.ncbi.nlm.nih.gov/pubmed/27060137
http://dx.doi.org/10.1093/nar/gkw139