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Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression

To improve the epigenomic analysis of tissues rich in 5-hydroxymethylcytosine (hmC), we developed a novel protocol called TAB-Methyl-SEQ, which allows for single base resolution profiling of both hmC and 5-methylcytosine by targeted next-generation sequencing. TAB-Methyl-SEQ data were extensively va...

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Detalles Bibliográficos
Autores principales: Ivanov, Maxim, Kals, Mart, Lauschke, Volker, Barragan, Isabel, Ewels, Philip, Käller, Max, Axelsson, Tomas, Lehtiö, Janne, Milani, Lili, Ingelman-Sundberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001587/
https://www.ncbi.nlm.nih.gov/pubmed/27131363
http://dx.doi.org/10.1093/nar/gkw316