Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair

DNA mismatch repair (MMR) is an evolutionarily-conserved process responsible for the repair of replication errors. In Escherichia coli, MMR is initiated by MutS and MutL, which activate MutH to incise transiently-hemimethylated GATC sites. MMR efficiency depends on the distribution of these GATC sit...

Descripción completa

Detalles Bibliográficos
Autores principales: Hermans, Nicolaas, Laffeber, Charlie, Cristovão, Michele, Artola-Borán, Mariela, Mardenborough, Yannicka, Ikpa, Pauline, Jaddoe, Aruna, Winterwerp, Herrie H.K., Wyman, Claire, Jiricny, Josef, Kanaar, Roland, Friedhoff, Peter, Lebbink, Joyce H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001592/
https://www.ncbi.nlm.nih.gov/pubmed/27174933
http://dx.doi.org/10.1093/nar/gkw411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001592/
https://www.ncbi.nlm.nih.gov/pubmed/27174933
http://dx.doi.org/10.1093/nar/gkw411

Ejemplares similares