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Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair
DNA mismatch repair (MMR) is an evolutionarily-conserved process responsible for the repair of replication errors. In Escherichia coli, MMR is initiated by MutS and MutL, which activate MutH to incise transiently-hemimethylated GATC sites. MMR efficiency depends on the distribution of these GATC sit...
Autores principales: | Hermans, Nicolaas, Laffeber, Charlie, Cristovão, Michele, Artola-Borán, Mariela, Mardenborough, Yannicka, Ikpa, Pauline, Jaddoe, Aruna, Winterwerp, Herrie H.K., Wyman, Claire, Jiricny, Josef, Kanaar, Roland, Friedhoff, Peter, Lebbink, Joyce H.G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001592/ https://www.ncbi.nlm.nih.gov/pubmed/27174933 http://dx.doi.org/10.1093/nar/gkw411 |
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