Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region

Pathogenic bacteria such as Haemophilus influenzae, a major cause of lower respiratory tract diseases, must cope with a range of electrophiles generated in the host or by endogenous metabolism. Formaldehyde is one such compound that can irreversibly damage proteins and DNA through alkylation and cro...

Descripción completa

Detalles Bibliográficos
Autores principales: Couñago, Rafael M., Chen, Nathan H., Chang, Chiung-Wen, Djoko, Karrera Y., McEwan, Alastair G., Kobe, Bostjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001606/
https://www.ncbi.nlm.nih.gov/pubmed/27307602
http://dx.doi.org/10.1093/nar/gkw543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001606/
https://www.ncbi.nlm.nih.gov/pubmed/27307602
http://dx.doi.org/10.1093/nar/gkw543

Ejemplares similares