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Accurate Morphology Preserving Segmentation of Overlapping Cells based on Active Contours
The identification of fluorescently stained cell nuclei is the basis of cell detection, segmentation, and feature extraction in high content microscopy experiments. The nuclear morphology of single cells is also one of the essential indicators of phenotypic variation. However, the cells used in expe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001623/ https://www.ncbi.nlm.nih.gov/pubmed/27561654 http://dx.doi.org/10.1038/srep32412 |