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Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE

SMC proteins constitute the core members of the Smc5/6, cohesin and condensin complexes. We demonstrate that Smc5/6 is present at telomeres throughout the cell cycle and its association with chromosome ends is dependent on Nse3, a subcomponent of the complex. Cells harboring a temperature sensitive...

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Detalles Bibliográficos
Autores principales: Moradi-Fard, Sarah, Sarthi, Jessica, Tittel-Elmer, Mireille, Lalonde, Maxime, Cusanelli, Emilio, Chartrand, Pascal, Cobb, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001636/
https://www.ncbi.nlm.nih.gov/pubmed/27564449
http://dx.doi.org/10.1371/journal.pgen.1006268