Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma

Interaction between tumor cells and stromal cells plays an important role in the growth and metastasis of colon cancer. We previously found that carcinoma‐associated fibroblasts (CAFs) expressed platelet‐derived growth factor receptor‐β (PDGFR‐β) and that PDGFR targeted therapy using imatinib or nil...

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Detalles Bibliográficos
Autores principales: Takigawa, Hidehiko, Kitadai, Yasuhiko, Shinagawa, Kei, Yuge, Ryo, Higashi, Yukihito, Tanaka, Shinji, Yasui, Wataru, Chayama, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001714/
https://www.ncbi.nlm.nih.gov/pubmed/26865419
http://dx.doi.org/10.1111/cas.12907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001714/
https://www.ncbi.nlm.nih.gov/pubmed/26865419
http://dx.doi.org/10.1111/cas.12907

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