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Curcumin reduces the expression of survivin, leading to enhancement of arsenic trioxide-induced apoptosis in myelodysplastic syndrome and leukemia stem-like cells

Low response, treatment-related complications and relapse due to the low sensitivity of myelodysplastic syndrome (MDS) and leukemia stem cells (LSCs) or pre-LSCs to arsenic trioxide (ATO), represent the main problems following treatment with ATO alone in patients with MDS. To solve these problems, a...

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Detalles Bibliográficos
Autores principales: Zeng, Yingjian, Weng, Guangyang, Fan, Jiaxin, Li, Zhangqiu, Wu, Jianwei, Li, Yuanming, Zheng, Rong, Xia, Pingfang, Guo, Kunyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001835/
https://www.ncbi.nlm.nih.gov/pubmed/27430728
http://dx.doi.org/10.3892/or.2016.4944