Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level

BACKGROUND: Human mesenchymal stem cells (MSC), during in vitro expansion, undergo a progressive loss of proliferative potential that leads to the senescent state, associated with a reduction of their “medicinal” properties. This may hampers their efficacy in the treatment of injured tissues. Qualit...

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Detalles Bibliográficos
Autores principales: Bellotti, Chiara, Capanni, Cristina, Lattanzi, Giovanna, Donati, Davide, Lucarelli, Enrico, Duchi, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001959/
https://www.ncbi.nlm.nih.gov/pubmed/27625981
http://dx.doi.org/10.1186/s40064-016-3091-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001959/
https://www.ncbi.nlm.nih.gov/pubmed/27625981
http://dx.doi.org/10.1186/s40064-016-3091-7

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