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Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
BACKGROUND: Human mesenchymal stem cells (MSC), during in vitro expansion, undergo a progressive loss of proliferative potential that leads to the senescent state, associated with a reduction of their “medicinal” properties. This may hampers their efficacy in the treatment of injured tissues. Qualit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001959/ https://www.ncbi.nlm.nih.gov/pubmed/27625981 http://dx.doi.org/10.1186/s40064-016-3091-7 |