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α-Synuclein deficiency promotes neuroinflammation by increasing Th1 cell-mediated immune responses

BACKGROUND: Increased α-synuclein immunoreactivity has been associated with inflammatory activity in multiple sclerosis (MS) lesions, but the function of α-synuclein in neuroinflammation remains unknown. The aim of this study was to examine the role of α-synuclein in immunological processes in murin...

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Detalles Bibliográficos
Autores principales: Ettle, Benjamin, Kuhbandner, Kristina, Jörg, Stefanie, Hoffmann, Alana, Winkler, Jürgen, Linker, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002168/
https://www.ncbi.nlm.nih.gov/pubmed/27565429
http://dx.doi.org/10.1186/s12974-016-0694-4