Statistical inference for time course RNA-Seq data using a negative binomial mixed-effect model

BACKGROUND: Accurate identification of differentially expressed (DE) genes in time course RNA-Seq data is crucial for understanding the dynamics of transcriptional regulatory network. However, most of the available methods treat gene expressions at different time points as replicates and test the si...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoxiao, Dalpiaz, David, Wu, Di, S. Liu, Jun, Zhong, Wenxuan, Ma, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002174/
https://www.ncbi.nlm.nih.gov/pubmed/27565575
http://dx.doi.org/10.1186/s12859-016-1180-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002174/
https://www.ncbi.nlm.nih.gov/pubmed/27565575
http://dx.doi.org/10.1186/s12859-016-1180-9

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